微创医学

【摘要】目的探讨全胸腔镜单向式肺叶切除术治疗早期非小细胞肺癌的临床疗效。方法将76例早期非小细胞肺癌患者随机分为两组，对照组38例，采用常规开胸术治疗；治疗组38例，以全胸腔镜单向式肺叶切除术治疗。比较两组围术期及术后相关指标的变化。结果两组手术时间比较，差异无统计学意义（P＞0.05）。治疗组术中出血量、术后住院时间短于对照组，胸腔引流量多于对照组，VAS评分低于对照组，两组比较，差异有统计学意义（P＜0.05）。治疗组术后并发症发生率为5.26%（2/38），明显低于对照组的28.95%（11/38），两组比较，差异有统计学意义（P＜0.05）。治疗组术后1年无瘤生存率为97.37%（37/38），对照组为94.74%（36/38），两组比较，差异无统计学意义（P＞0.05）。结论应用全胸腔镜单向式肺叶切除术治疗早期非小细胞肺癌不能降低患者生存期，但可减轻对患者的创伤，有利于其术后康复。

【Abstract】 ObjectiveTo explore the clinical efficacy of singledirection complete thoracoscopic lobectomy for the treatment of earlystage nonsmall cell lung cancer. MethodsOf 76 patients with nonsmall cell lung cancer, 38 cases were enrolled as control group and received routine thoracotomy, and 38 cases were enrolled as treatment group and received singledirection complete thoracoscopic lobectomy. The changes of perioperative and postoperative indicators were compared between the two groups. ResultsThere was no significant difference in the operative duration between the two groups（P＞0.05）. Compared with the control group, the intraoperative blood loss and postoperative hospital stay were less, the volume of chest drainage was more and VAS was lower in the treatment group(P＜0.05). The incident rate of postoperative complications in the observation group was lower than that in the control group ［5.26%（2/38）vs 28.95%（11/38）,P＜0.05］. There was no significant difference in the postoperative oneyear diseasefree survival between the treatment group and the control group ［97.37%（37/38） vs 94.74%（36/38）, P＞0.05］ . ConclusionFor earlystage nonsmall cell lung cancer, singledirection complete thoracoscopic lobectomy for the treatment can nor decrease prolonged the patients′ survival time, but can relieve the trauma and is benefit to the postoperative recovery.