Objective To investigate the therapeutic effects of 3D laparoscopic-guided salpingotomy with embryo extraction and suturing in the treatment of tubal pregnancy. Methods A total of 66 patients with tubal pregnancy were selected as the research subjects. According to the order of their admission, the patients were divided into an observation group and a control group, with 33 cases in each group. The observation group was treated with 3D laparoscopic-guided salpingotomy with embryo extraction and suturing, while the control group was treated with 2D laparoscopic-guided salpingotomy with embryo extraction and suturing. The following parameters were compared between the two groups of patients: operation time, intraoperative blood loss, intraoperative electrocoagulation times, length of postoperative hospital stay, postoperative persistent ectopic pregnancy, levels of ovarian function indicators (estradiol, follicle stimulating hormone [FSH], anti-Müllerian hormone [AMH]), postoperative tube patency rate, and fertility prognosis. Results In the observation group, the operation time was shorter than that in the control group, and the intraoperative blood loss and intraoperative electrocoagulation times were less than those in the control group (P<0.05). No cases of postoperative persistent ectopic pregnancy were observed in either group, and there was no statistically significant difference in the length of postoperative hospital stay between the two groups (P>0.05). At 2 months postoperatively, there was no statistically significant difference in the serum levels of estradiol, FSH, and AMH between the observation group and its preoperative levels (P>0.05). However, the serum levels of estradiol and AMH in the observation group were higher than those in the control group, while its serum FSH level was lower than that in the control group. In contrast, the serum levels of estradiol and AMH in the control group were lower, and its serum FSH level was higher than their preoperative level (P<0.05). At 2 months postoperatively, the tube patency rate of patients in the observation group was higher than their in the control group; within 1 year postoperatively, the intrauterine natural pregnancy rate of the observation group was also higher than that in the control group (P<0.05). While there was no statistically significant difference in the recurrent ectopic pregnancy rate between the two groups (P>0.05). Conclusion Compared with 2D laparoscopy, performing salpingotomy with embryo extraction and suturing under 3D laparoscopy in the treatment of patients with tubal pregnancy can not only shorten the operation time, reduce intraoperative blood loss and intraoperative electrocoagulation times, and have a smaller impact on ovarian function, but also improve the postoperative fallopian tube patency rate and intrauterine pregnancy rate.

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