当前位置:首页 / 基于文献计量学分析近十年中医药治疗甲状腺癌的研究热点及趋势
论著 | 更新时间:2026-01-04
|
基于文献计量学分析近十年中医药治疗甲状腺癌的研究热点及趋势
Bibliometric analysis of research hotspots and trends in traditional Chinese medicine for thyroid cancer over the past decade

微创医学 页码:545-554

作者机构:1 广西医科大学第一临床医学院,广西南宁市 530000;2 广西医科大学第一附属医院康复医学科,广西南宁市 530021

DOI:10.11864/j.issn.1673.2025.05.08

  • 中文简介
  • 英文简介
  • 参考文献

目的 基于文献计量学分析近十年中医药治疗甲状腺癌研究热点及趋势。方法 检索2014年1月至2024年12月中国知网及Web of Science数据库中的相关文献,采用CiteSpace 6.1.R6软件对纳入的相关文献进行作者、机构、关键词的共现、聚类及突现分析。结果 2014—2024年,两个数据库共收录中医药治疗甲状腺癌的相关文献264篇,年度发文量总体呈波动上升趋势,研究力量集中于中医药院校,多团队合作较薄弱。中文文献关键词频次≥5的共有23个,出现频次最高的关键词是甲状腺癌、甲状腺癌术后、左甲状腺素钠片;英文文献关键词频次≥5的共有12个,出现频次最高的关键词是carcinoma(癌症),apoptosis(凋亡),expression(表达)。中文文献关键词共形成10个聚类,分别为甲状腺癌术后、左甲状腺素钠片、中医证候积分、抑郁、用药规律、免疫功能、细胞增殖、远期疗效、肿瘤标志物、高脂血症。英文文献关键词共形成6个聚类,分别为antioxidant(抗氧化剂)、growth(生长)、 post-operative pain(术后疼痛)、papillary thyroid cancer(乳头状甲状腺癌)、multicolor emitting carbon dots(多色荧光碳点)、astaxanthin(虾青素)。关键词突现分析结果显示,甲状腺功能、网络药理学、名医经验、甲状腺球蛋白、131I治疗、proliferation(增殖)、growth(生长)、磷脂酰肌醇3激酶-Akt激酶(PI3K-Akt)是中医药治疗甲状腺癌研究领域的主要研究热点。结论 中英文文献研究热点存在明显分化,中文文献研究侧重于术后康复、证候规律与名医经验,英文文献研究则聚焦于凋亡、增殖及PI3K/Akt等分子机制。未来应加强多学科交叉与合作推动中医药在甲状腺癌精准治疗中的转化应用。

Objective To analyze the research hotspots and trends in traditional Chinese medicine for thyroid cancer over the past decade based on bibliometrics. Methods Relevant studies were retrieved from the China National Knowledge Infrastructure and Web of Science databases between January 2014 and December 2024, and CiteSpace 6.1.R6 software was employed to perform co-occurrence, cluster, and burst analyses of authors, institutions, and keywords in the included literature. Results A total of 264 relevant studies on traditional Chinese medicine for thyroid carcinoma were retrieved from the two databases between 2014 and 2024. The annual number of published studies showed an overall fluctuating upward trend, with research efforts concentrated in traditional Chinese medicine colleges and universities. However, multi-team collaboration remained relatively weak. A total of 23 keywords with a frequency of ≥5 were identified in the Chinese-language literature, with the top three most frequently occurring keywords being "thyroid cancer", "postoperative thyroid cancer", and "levothyroxine sodium tablets". In the English-language literature, 12 keywords had a frequency of ≥5, and the most prevalent ones were carcinoma, apoptosis, and expression. In the Chinese-language literature, the keywords formed 10 clusters, namely "postoperative thyroid cancer", "levothyroxine sodium tablets", "traditional Chinese medicine syndrome score", "depression", "medication rules", "immune function", "cell proliferation", "long-term efficacy", "tumor markers", and "hyperlipidemia". In the English-language literature, 6 clusters were identified from the keywords, namely antioxidant, growth, post-operative pain, papillary thyroid cancer, multicolor emitting carbon dots, and astaxanthin. Burst keyword analysis revealed that "thyroid function", "network pharmacology", "famous physicians' experience", "thyroglobulin", "131I therapy", proliferation, growth, and phosphoinositide 3-kinase-Akt kinase (PI3K/Akt) are the key research hotspots in the field of traditional Chinese medicine for thyroid cancinoma. Conclusion Research hotspots exhibited significant divergence between Chinese- and English-language literatures: the Chinese-language studies focused on postoperative rehabilitation, syndrome patterns, and famous physicians' experience, while the English-language studies centered on apoptosis, proliferation, and molecular mechanisms such as the PI3K-Akt. Future efforts should prioritize strengthening multidisciplinary intersection and collaboration to promote the translational application of traditional Chinese medicine in the precise treatment of thyroid cancer.

33

浏览量

5

下载量

0

CSCD

工具集