ObjectiveTo study the clinical effect of percutaneous transhepatic cholangioscopy (PTCS) and percutaneous nephroscopy (PCN) combined with ultrasonic lithotripsy through biliary fistula sinus tract in the treatment of bile duct stones. MethodsClinical data of 64 patients with intrahepatic and extrahepatic bile duct stones admitted from June 2016 to June 2018 were retrospectively analyzed. All 64 patients were divided into PTCS group or PCN group according to different treatment methods (on the basis of ultrasonic lithotripsy through biliary fistula sinus tract treatment), with 32 cases in each group. Then another 32 intrahepatic and extrahepatic bile duct stones patients undergoing conventional operation from January 2015 to June 2016 were selected as convention group. The clinical indexes and the incidence of complications were compared between the three groups, and the liver function of the three groups before and 6 months after operation was analyzed. ResultsCompared to the convention group, patients in the PTCS and PCN groups obtained shorter operation duration, hospital stay, lower intraoperative bleeding volume and re-occurrence rate of calculi, whereas a higher removal rate of calculi (all P＜0.05); however, there were no statistically significant differences in the abovementioned indicators between the PTCS group and the PCN group (all P＞0.05). Six months after operation, the levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the three groups decreased significantly, and the levels were lower in the PTCS and PCN groups than in the conventional group (all P＜0.05), but there was no statistically significant difference between the PTCS and PCN groups (P＞0.05). ConclusionBoth PTCS and PCN in a combination with ultrasonic lithotripsy through biliary fistula sinus tract can prominently improve the clinical indicators and liver function in patients with intrahepatic and extrahepatic bile duct stones.

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